Some registry entries may require account privileges beyond what a standard user would have. For information, see the "Editing PC-DMIS Registry Entries" topic. That topic discusses the different account privileges. It also provides a description of each icon that appears next to each registry entry in the PC-DMIS Settings Editor.
You may see two sections with the same base name, but one with a prefix of "USER_", for example USER_AutoFeatures. Settings that require a general user privilege are stored in these sections. Interface settings that require administrator privileges to change them are stored in the regular section name, for example AutoFeatures.